Natural attenuated strain of infectious laryngotracheitis virus with good safety and good immunogenicity and use thereof

Abstract

Provided is a natural attenuated strain of infectious laryngotracheitis virus attenuated strain (ITLV) with good safety and good immunogenicity. The natural attenuated strain, designated as ILTV FJ19, has been deposited in the China Center for Type Culture Collection on Nov. 29, 2023 with a deposit number of CCTCC NO: V2023109, the deposit address is No. 299, Bayi Road, Wuchang District, Wuhan City, Hubei Province. Experiments have shown that the avian infectious laryngotracheitis virus ILTV FJ19 strain has a stable passaging ability, may adapt to inoculation via the allantoic cavity route, has good safety and good immunogenicity when inoculated to 14-day-old SPF chickens. The strain may be used through eye-drop vaccination or oral administration, making it a candidate strain for attenuated live vaccine against ILTV.

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