Development of carbohydrate-based anti-salmonella vaccines
AssigneesBoard of Trustees of Michigan State University, University of Maryland, Baltimore
InventorsXuefei Huang, Xingling Pan, Chang-Xin Huo, Scott Michael Baliban, Sharon Mei Tennant
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Abstract
Provided herein are vaccine compositions comprising Salmonella antigens conjugated to a capsid, wherein said capsid comprises wild type or native sequence, or said capsid may comprise at least one mutation, such as a non-natural mutation; such compositions being useful in the treatment and prevention of a Salmonella infection (salmonellosis), gastroenteritis, typhoid fever, and/or paratyphoid fever; and may be effective against multiple strains of Salmonella.
Claims22
A vaccine composition comprising a Salmonella antigen conjugated to a capsid, wherein said capsid comprises at least one non-natural mutation.
Dependencies are inferred from the claim text.