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US 2026/0306583 A1Published application
Use of annexin v as a method to block tumor induced immunosuppression of the innate immune response
AssigneeThe Board of Trustees of the Leland Stanford Junior University
InventorFrancis Gerard Blankenberg
Life of this patent
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Abstract
Methods are provided for treating a subject with cancer, with a therapeutic dose of annexin V to the subject.
Claims23
A method of increasing the immune response to a tumor in an individual with cancer, the method comprising:
- administering a course of therapy to the individual by parenteral administration of an effective dose of an annexin V agent,
- wherein the annexin V agent is an annexin V protein that binds to phosphatidylserine (PS) and which comprises an amino sequence which has at least 95% sequence identity to the amino acid sequence of human annexin V protein, and
- wherein the individual also receives another cancer treatment modality.
2-14. (canceled)
(canceled)
Dependencies are inferred from the claim text.