Treatment of cerebral cavernous malformations and cerebral aneurysms with rho kinase inhibitors

A method of slowing lesion formation or expansion in a patient suffering from a neurological condition, the method comprising:

• orally administering a pharmaceutical formulation comprising therapeutically effective amount of a rho kinase inhibitor to the patient, wherein the rho kinase inhibitor is Compound 1, having the structure:
• or a pharmaceutically acceptable salt thereof, wherein administering the pharmaceutical formulation to the patient results in a reduction of one or more symptoms of the neurological condition;
• wherein the neurological condition is selected from cerebral cavernous malformation, cavernous angioma, cerebral aneurysm, cavernoma, or combinations thereof;
• and
• wherein the patient's lesion formation or expansion is slowed.