Centrifugal screening device
AssigneeFeng Chia University
InventorsChih-Hsin Shih, Chia-Tse Shih
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AssigneeFeng Chia University
InventorsChih-Hsin Shih, Chia-Tse Shih
Estimating the term…
The present invention relates to a centrifugal screening device composed of two fluidly connected portions, namely an inner disk and an outer ring. The inner disk includes a tree-like branched structure capable of providing a concentration gradient for cell growth. The outer ring includes multiple sample chambers for placing cells and allows repeated quantitative dosing and evacuation of culture medium. The present invention distributes different reagents into multiple mixed concentrations with gradient distributions through the tree-like structure of the inner disk, thereby enabling drug concentration testing on cells. Furthermore, the concept of combining the inner disk and the outer ring is applied to interchangeable functional unit disks and integrated into an automated centrifugal screening platform. This system establishes an automated workflow and reduces the cost associated with conventional cell-drug screening.
A centrifugal screening device comprising an inner disk and an outer ring in fluid communication, wherein:
Dependencies are inferred from the claim text.