Photocrosslinkable recombinant bacterial collagen-like proteins
AssigneeEvonik Operations GmbH
InventorsYunxiao LIU, Eva Yihua LOO, Ann RITTER
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Abstract
Recombinant bacterial collagen-like protein with an amino acid sequence that is at least ≥60% identical to the amino acid sequence of SEQ ID NO:1 characterized in that the amino acid sequence comprises a deletion of at least 38 amino acids at the N-terminus of the amino acid sequence of SEQ ID NO:1 and that the recombinant collagen-like protein is functionalized with ethylenic unsaturated groups.
Claims16
Recombinant bacterial collagen-like protein with an amino acid sequence that is at least ≥60% identical to the amino acid sequence of SEQ ID NO:1 characterized in that the amino acid sequence comprises a deletion of at least 38 amino acids at the N-terminus of the amino acid sequence of SEQ ID NO:1 and that the recombinant collagen-like protein is functionalized with ethylenic unsaturated groups.
Process for functionalizing a recombinant bacterial collagen-like protein with an amino acid sequence at least 98% identical to the amino acid sequence of SEQ ID NO:2, SEQ ID NO:3 or SEQ ID NO:4 with (meth)acrylic anhydride, characterized in that functionalization is carried out at a molar ratio of (meth)acrylic anhydride to amine groups of the recombinant bacterial collagen-like protein between 0.5:1 and 5:1.
Dependencies are inferred from the claim text.