Peptides with lipolytic, anti-lipogenic, antifibrotic and anti-inflammatory activity

A peptide, or a pharmaceutically acceptable salt thereof, wherein the peptide has a length of 10 to 40 amino acids, each one of the amino acids being a L- or D-amino acid, and consists of a peptide fragment F1 and, additionally:

• of a peptide fragment F2 at the N-terminal end of peptide fragment F1 and/or of a peptide fragment F3 at the C-terminal end of peptide fragment F1, wherein,
• i) peptide fragment F1 has SEQ ID NO. 9:
• TWDPEGVIFY or is a sequence variant thereof that has at least 80% sequence identity with SEQ ID NO.9, wherein each one of the amino acids of peptide fragment F1 is a L- or D-amino acid,
• ii) peptide fragment F2 has SEQ ID NO. 13 (TKTSSSFEVR) or is a sequence variant thereof with at least 80% sequence identity with SEQ ID NO.13;
• or has SEQ ID NO. 14 (VMTFDLTKITKTSSSFEVR) or is a sequence variant thereof with at least 80% sequence identity with SEQ ID NO.14;
• and wherein each one of the amino acids of peptide fragment F2 is a L- or D-amino acid;
• and
• iii) peptide fragment F3 has SEQ ID NO. 4 (GDTNPKDDWF) or is a sequence variant thereof with at least 80% sequence identity with SEQ ID NO.4;
• or has SEQ ID NO. 15 (GDTNPKDDWFMLGLRDGRPE) or is a sequence variant thereof with at least 80% sequence identity with SEQ ID NO.15;
• and wherein each one of the amino acids of peptide fragment F3 is a L- or D-amino acid.