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US 2026/0295552 A1Published application
Parallel substrates for multiplexing biomolecule processing
AssigneeTwist Bioscience Corporation
InventorsAnthony DE LA CRUZ, Pranav SUNDARAM, Roger RUDOFF
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Abstract
Described herein are devices, systems, methods for processing biomolecules on a plurality of parallel substrates. A device can comprise a first substrate and a second substrate that can be substantially parallel. Each substrate can comprise a functionalized surface facing one another. The device may further comprise one or more fluidic interfaces and one or more spacers separating a plurality of substrates.
Claims21
A device for processing a plurality of biomolecules comprising:
- a first substrate comprising a first surface functionalized for association with a first building block of the plurality of biomolecules;
- and
- a second substrate comprising a second surface functionalized for association with a second building block of the plurality of biomolecules, wherein the second surface faces the first surface.
A device for processing a plurality of biomolecules comprising:
- a top substrate comprising a first top surface and a first bottom surface, wherein the first bottom surface is functionalized for association with a building block of the plurality of biomolecules;
- a middle substrate comprising a second top surface and a second bottom surface functionalized for association with a building block of the plurality of biomolecules, wherein the second top surface and the first bottom surface define a first cavity;
- a bottom substrate comprising a third top surface and a third bottom surface, the third top surface functionalized for association with a building block of the plurality of the plurality of biomolecules, wherein the third top surface and the second bottom surface define a second cavity.
Dependencies are inferred from the claim text.