Back to results
US 2026/0295462 A1Published application
Separation Matrix and a Method of Separating Antibodies
AssigneeCytiva BioProcess R&D AB
InventorsKarol Maciej Lacki, Hans Blom, Helena Skoglar, Linus Laurin
Life of this patent
Estimating the term…
Abstract
The invention discloses a chromatography system and method comprising a separation matrix comprised of porous spherical particles to which antibody-binding protein ligands have been covalently immobilized, wherein the density of said ligands is in the range of 10.5-15 mg/ml and the volume-weighted median diameter of said particles is in the range of 30-55 μm.
Claims9
A method of separation of antibodies by affinity chromatography, which method comprises the steps of:
- a) conveying a process feed through at least a first chromatography column according to claim 1, to adsorb antibodies from said feed;
- b) washing said first chromatography column;
- c) conveying an eluent through said first chromatography column to elute antibodies;
- and
- d) recovering said eluent with antibodies.
2 more elements
The method of claim 3, which is carried out in the chromatography system of claim 10.
Dependencies are inferred from the claim text.