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US 2026/0295303 A1Published application
Machine learning approach for adaptive radiation therapy using composite imaging slices
AssigneeElekta Limited
InventorsFrancois Paul George Rene Hebert, Sebastien Tremblay
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Abstract
A radiation therapy treatment plan can be adjusted concurrently with delivery of the therapy in order to compensate for changes in a position of a target. For example, at least two image slices, taken from different in-plane directions, can be used to estimate motion in a through-plane direction substantially orthogonal to the in-plane directions. A machine learning model can be trained with interpolations from a sequence of in-plane image slices, the motion estimated therefrom in the through-plane direction, or both to predict 3D motion.
Claims19
A computing device for motion tracking during radiation treatment of a patient, the computing device including a processor and a memory device, the memory device including instructions that, when executed by the processor, cause the computing device to:
- receive, during a radiation session, a first image set corresponding to a specified anatomical structure of the patient, the first image set of the specified anatomical structure captured at different times at a first plane;
- receive, during the radiation session, a second image set corresponding to the specified anatomical structure of the patient, the second image set of the specified anatomical structure captured at different times at a second plane oriented at an angle to the first plane;
- identify a first initial trajectory based on an interpolation of respective registration points of the specified anatomical structure for first and second image slices of the first image set, the first initial trajectory having an in-plane direction with at least one of the first and second planes;
- identify a second initial trajectory based on an interpolation of respective registration points of the specified anatomical structure for a first and second image slices of the second image set, the second initial trajectory in an in-plane direction with at least one of the first and second planes;
- determine, based on the first and second initial trajectories, a third initial trajectory including a through-plane coordinate corresponding with the first plane and a through-plane coordinate corresponding with the second plane;
- train a model, using training data obtained during the radiation session, the training data including the first, second, and third trajectories, to estimate a three dimensional (3D) position of the specified anatomical structure, the 3D position including a coordinate in a through-plane direction based on the respective through-plane coordinates corresponding with the first and second planes;
- output the model for use in generating an updated therapy protocol;
- and
- generate, using the model, an updated therapy protocol to control delivery of a beam of radiation.
6 more elements
A computer-implemented method for motion tracking during radiation treatment of a patient, the method comprising:
- receiving, during a radiation session, a first image set corresponding to a specified anatomical structure of the patient, the first image set of the specified anatomical structure captured at different times at a first plane;
- receiving, during the radiation session, a second image set corresponding to the specified anatomical structure of the patient, the second image set of the specified anatomical structure captured at different times at a second plane oriented at an angle to the first plane;
- identifying a first initial trajectory based on an interpolation of respective registration points of the specified anatomical structure for first and second image slices of the first image set, the first initial trajectory having an in-plane direction with at least one of the first and second planes;
- identifying a second initial trajectory based on an interpolation of respective registration points of the specified anatomical structure for first and second image slices of the second image set, the second initial trajectory in an inplane direction with at least one of the first and second planes;
- determining, based on the first and second initial trajectories, a third initial trajectory including a through-plane coordinate corresponding with the first plane and a through-plane coordinate corresponding with the second plane;
- training a model, using training data obtained during the radiation session, the training data including the first, second, and third trajectories, to estimate a three dimensional (3D) position of the specified anatomical structure, the 3D position including a coordinate in a through-plane direction based on the respective through-plane coordinates corresponding with the first and second planes;
- and
- outputting the model for use in generating an updated therapy protocol.
5 more elements
A method for motion tracking during radiation treatment of a patient, the method comprising:
- receiving, during a radiation session, a first image set corresponding to a specified anatomical structure of the patient, the first image set of the specified anatomical structure captured at different times at a first plane;
- identifying a first initial trajectory based on an interpolation of respective registration points of the specified anatomical structure for first and second image slices of the first image set, the first initial trajectory having an in-plane direction with the first plane;
- determining, based on the first initial trajectory, a through-plane initial trajectory including a through-plane coordinate corresponding with the first plane and a through-plane coordinate corresponding with the second plane;
- estimating, using the first initial trajectory and the through-plane initial trajectory as an input to a trained model, a three dimensional (3D) position of the specified anatomical structure, the 3D position including a coordinate in a through-plane direction based on the respective through-plane coordinates corresponding with the first and second planes;
- generating an updated therapy protocol based on predicted movement of the specified anatomical structure;
- and
- establishing or adjusting, based on the predicted movement, a shape of a radiotherapy beam delivered to the specified anatomical structure.
4 more elements
Dependencies are inferred from the claim text.