Local dose heterogeneity metric for spatially fractionated radiotherapy
AssigneeSiemens Healthineers International AG
InventorPierre LANSONNEUR
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Abstract
A method is described for planning and administering a spatially fractionated radiotherapy treatment plan. The method may include receiving the treatment plan that includes a heterogenous radiotherapy dose that has a plurality of local maximum doses and a plurality of local minimum doses. The method may include generating an upper heterogenic curve based at least in part on the plurality of local maximum doses and generating a lower heterogenic curve based at least in part on the plurality of local minimum doses. The method may include determining a dose envelope bounded by the upper heterogenic curve and the lower heterogenic curve. The method may include generating a local dose contrast based on the upper and lower heterogenic curves of the dose envelope.
Claims20
A method for adjusting a spatially fractionated radiotherapy treatment plan, the method comprising:
- receiving, by one or more processors, a radiotherapy treatment plan to administer to a target tissue, the radiotherapy treatment plan having a heterogeneous dose comprising:
- a plurality of local maximum doses, and
- a plurality of local minimum doses;
- generating, by the one or more processors, (i) an upper heterogenic curve based at least in part on the plurality of local maximum doses and (ii) a lower heterogenic curve based at least in part on the plurality of local minimum doses;
- determining, by the one or more processors, a dose envelope of the radiotherapy treatment plan bounded by the upper heterogenic curve and the lower heterogenic curve;
- and
- generating, by the one or more processors, a local dose contrast of the dose envelope at a position within the dose envelope, wherein the one or more processors are configured to adjust a treatment parameter of the radiotherapy treatment plan based at least in part on the generated local dose contrast.
A system for adjusting a spatially fractionated radiotherapy treatment plan, the system comprising:
- one or more processors;
- and
- a computer-readable, non-transitory storage medium containing instructions that, when executed by the one or more processors, cause the one or more processors to perform a method comprising:
- receiving a radiotherapy treatment plan to administer to a target tissue, the radiotherapy treatment plan having a heterogeneous dose comprising:
- a plurality of local maximum doses, and
- a plurality of local minimum doses;
- generating (i) an upper heterogenic curve based at least in part on the plurality of local maximum doses and (ii) a lower heterogenic curve based at least in part on the plurality of local minimum doses;
- determining a dose envelope of the radiotherapy treatment plan bounded by the upper heterogenic curve and the lower heterogenic curve;
- and
- generating a local dose contrast of the dose envelope at a position within the dose envelope, wherein the one or more processors are configured to adjust a treatment parameter of a radiotherapy treatment plan based at least in part on the generated local dose contrast.
A computer-readable, non-transitory storage medium containing instructions for adjusting a spatially fractionated radiotherapy treatment plan and, when executed by one or more processors, cause the one or more processors to perform a method comprising:
- receiving a radiotherapy treatment plan to administer to a target tissue, the radiotherapy treatment plan having a heterogeneous dose comprising:
- a plurality of local maximum doses, and
- a plurality of local minimum doses;
- generating (i) an upper heterogenic curve based at least in part on the plurality of local maximum doses and (ii) a lower heterogenic curve based at least in part on the plurality of local minimum doses;
- determining a dose envelope of the radiotherapy treatment plan bounded by the upper heterogenic curve and the lower heterogenic curve;
- and
- generating a local dose contrast of the dose envelope at a position within the dose envelope, wherein the one or more processors are configured to adjust a treatment parameter of a radiotherapy treatment plan based at least in part on the generated local dose contrast.
Dependencies are inferred from the claim text.