Composition for preventing or treating capsular contracture caused by implant surgery and use thereof

Abstract

The present disclosure relates to PCL electrospun fibers comprising fish oil and montelukast sodium, a method for preparing the same, and use thereof. According to the present disclosure, the electrospun fibers comprising fish oil and montelukast sodium may significantly reduce collagen over-deposition or fibrosis over-production when implanted into an animal model, inhibit the activation of myofibroblasts, develop fibrosis of the implanted surrounding tissue to a late stage, formation, suppress inhibit bacterial adhesion and biofilm inflammatory cytokines, and stabilize a tissue structure by balancing tissue repair and fibrosis, thereby significantly treating capsular contracture. Therefore, the present disclosure may be effectively used for the prevention, improvement, or treatment of capsular contracture.

Dependencies are inferred from the claim text.