Back to results
US 2026/0295113 A1Published application
Sealants for tissue closure
AssigneeEthicon, Inc.
InventorsSalim A. Ghodbane, Sai Veruva, Mark Neubauer
Life of this patent
Estimating the term…
Loading patent…
Loading patent…
AssigneeEthicon, Inc.
InventorsSalim A. Ghodbane, Sai Veruva, Mark Neubauer
Estimating the term…
The invention relates to biodegradable bilayer sealants for tissue closure. The sealants of the invention are composed of two layers with different compliances. The layer in immediate contact with the tissue has high compliance. The second layer located immediately above the first sealant layer has low compliance, i.e. the sealant is much stiffer. The burst pressure of the bilayer sealants is enhanced relative to either a single layer elastic sealant or a single layer stiff sealant. The improved sealant compositions herein provide a water-tight seal, can access hard to reach tears, be applied in a dry or wet environment, are low-swelling, and can repair a range of incision or tear sizes. The bilayer sealants are particularly useful for sutureless dural closure or as adjuncts to sutured dural closure. Also provided herein are methods of preparing and using the biodegradable sealant compositions.
A biodegradable bilayer sealant for tissue closure comprising a first layer comprising an elastic polymeric composition and a second layer comprising a stiff polymeric composition wherein a ratio of layer thickness of the elastic polymeric composition to stiff polymer composition is from about 1:1 to about 3:1, respectively.
A kit for preparing a biodegradable bilayer sealant for closure of a tissue comprising:
Dependencies are inferred from the claim text.