Aptamer-based sustained release of therapeutic agents
AssigneeChildren's Medical Center Corporation
InventorsChristopher B. Weldon, Daniel S. Kohane, Dali Wang, Xiangang Huang
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Abstract
The present disclosure provides compositions comprising an aptamer and a molecular payload, wherein the aptamer is a sustained release carrier for the molecular payload. The molecular payload may be a therapeutic agent. The compositions thus provide a means of controlled and prolonged delivery of therapeutic agents. The present disclosure further provides kits comprising the compositions, methods of treating or preventing a disease or disorder, and methods of preparing the compositions.
Claims51
A composition comprising an aptamer and a molecular payload, wherein the molecular payload is bound to the aptamer, and wherein the aptamer is a sustained release carrier for the molecular payload.
Dependencies are inferred from the claim text.