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US 2026/0294904 A1Published application
Tablet comprising 6-((5-methyl-3-(6-methylpyridin-3-yl)isoxazol-4-yl)methoxy)- n-(tetrahydrapyran-4-yl)pyridazine-3-carboxamide
AssigneeHoffmann-La Roche Inc.
InventorsFelix DITZINGER, Reto MAURER
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Abstract
The present invention relates to a tablet comprising 6-((5-methyl-3-(6-methylpyridin-3-yl)isoxazol-4-yl)methoxy)-N-(tetrahydropyran-4-yl)pyridazine-3-carboxamide, to processes for its preparation, kits comprising it, and its use in medical treatment.
Claims32
A tablet comprising a kernel and optionally a coating, wherein said kernel comprises:
- (i) the API 6-((5-methyl-3-(6-methylpyridin-3-yl)isoxazol-4-yl)methoxy)-N-(tetrahydropyran-4-yl)pyridazine-3-carboxamide (I), or a pharmaceutically acceptable salt thereof,
- (ii) a superdisintegrant;
- (iii) a first filler;
- (iv) a second filler;
- (v) a glidant;
- and
- (vi) a lubricant;
- wherein the amount of API is ≤25%±1% relative to the total weight of the kernel, preferably ≤20%±1% relative to the total weight of the kernel;
- and
- wherein said kernel does not comprise lactose.
7 more elements
The invention as described hereinbefore.
Dependencies are inferred from the claim text.