Methods for treating cholestasis
AssigneeMirum Pharmaceutical, Inc.
InventorsThomas Jaecklin, Alejandro Dorenbaum
Life of this patent
Estimating the term…
Abstract
Provided herein are methods for treating cholestasis in a subject having a liver disease. The method includes administering to the subject an Apical Sodium-dependent Bile Acid Transporter (ASBTI). More specifically, the present invention relates to methods for treating cholestasis in a subject where the method includes administering an ASBTI to a subject at a dose of at least 10 μg/kg/day.
Claims21
-102. (canceled)
A method for treating or ameliorating primary biliary cirrhosis (PBC) in a subject comprising administering to the subject volixibat, or a pharmaceutically acceptable salt thereof, in an amount from about 20 mg/day to about 200 mg/day.
A method for treating or ameliorating cholestatic pruritus in a subject having primary biliary cirrhosis (PBC), the method comprising administering to the subject volixibat, or a pharmaceutically acceptable salt thereof, in an amount from about 20 mg/day to about 200 mg/day.
Dependencies are inferred from the claim text.