Pharmaceutical combinations and compositions thereof comprising antibacterial agents
OwnerVaishali Vikas GUPTE, Jaideep Ashok GOGTAY +1inventors
InventorsVaishali Vikas GUPTE, Jaideep Ashok GOGTAY, Sandesh Vishwanath SAWANT
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Abstract
The present invention relates to the combination of meropenem and one or more antibiotic resistance breakers, pharmaceutical compositions containing the same, and methods for treating bacterial infections that include administering the same. Particularly, it relates to a pharmaceutical composition comprising (a) meropenem, (b) avibactam, and (c) EDTA.
Claims21
-25. (canceled)
A pharmaceutical composition comprising (a) an effective amount of meropenem, (b) an effective amount of avibactam, and (c) an effective amount of EDTA.
A method of treating bacterial infection in a subject, said method comprising administering to said subject an effective amount of (a) meropenem, (b) avibactam, and (c) EDTA.
A method for treating a bacterial infection in pediatric patients, said method comprising administering to said subject a daily dose of (a) meropenem from about 10 mg/kg to about 40 mg/kg, (b) avibactam from about 10 mg/kg to about 12.5 mg/kg, and (c) EDTA from about 1.85 mg/kg to about 3.7 mg/kg.
Dependencies are inferred from the claim text.