Back to results
US 2026/0294834 A1Published application
Primate carbonic anhydrase iv binding peptides and aavs
AssigneeCalifornia lnstitute of Technology
InventorsViviana Gradinaru, Changfan Lin, Xinhong Chen, Timothy F. Shay
Life of this patent
Estimating the term…
Abstract
Disclosed herein include novel blood-brain barrier (BBB)-crossing receptors on the BBB interface, targeting peptides and derivatives thereof capable of binding to the novel receptors, and related methods of using the receptors to increase the permeability of the BBB and to deliver an agent to a nervous system (e g. CNS).
Claims20
A carbonic anhydrase IV-binding peptide selected from the group consisting of the carbonic anhydrase IV-binding peptides listed in Tables 1, 3, 4, and 5.
Dependencies are inferred from the claim text.