Pharmaceutical composition comprising glp-1 receptor agonist, gip/glp-1 receptor agonist and/or glp-1/gip/gcg receptor triple agonist

Abstract

The present invention provides a pharmaceutical composition, comprising: microspheres containing one or more selected from a GLP-1 receptor agonist, a GIP/GLP-1 receptor agonist and a GLP-1/GIP/GCG receptor triple agonist; and one or more pharmaceutically acceptable first carriers selected from the group consisting of a fluid oil containing a fatty acid ester, a surfactant and a polyhydric alcohol. The microspheres of the pharmaceutical composition remain stable for a long period of time in a suspension formulation, and the microspheres stored for a long period of time exhibit excellent dissolution characteristics. In addition, the pharmaceutical composition exhibits the effects of increasing bioavailability and reducing the dosage to be administered.

Dependencies are inferred from the claim text.