Dry powder formulations of epinephrine and associated methods
AssigneeBelhaven BioPharma Inc.
InventorsScott Lyman, Barry Bleske, Ted William Lanpher
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Abstract
Provided herein are dry powder formulations comprising epinephrine alone or in combination with at least one enabling agent suitable for nasal application. Also provided are unit dose forms and devices comprising such formulations and methods of using such formulations for the treatment of various conditions including anaphylaxis, anaphylactoid reaction, respiratory conditions, hemodynamic collapse, and for administration during cardiopulmonary arrest and other life-threatening conditions.
Claims20
A dry powder pharmaceutical composition comprising:
- a sole active ingredient, wherein the sole active ingredient consists of epinephrine or a pharmaceutically acceptable salt thereof,
- a citrate;
- and
- a carrier.
A method for intranasal administration of a dry powder pharmaceutical composition comprising:
- intranasally administering a dose of a dry powder pharmaceutical composition;
- wherein the dry powder pharmaceutical composition comprises a sole active ingredient a carrier;
- wherein the sole active ingredient consists of epinephrine or a pharmaceutically acceptable salt thereof.
A dry powder pharmaceutical composition comprising:
- a sole active ingredient, wherein the sole active ingredient consists of epinephrine or a pharmaceutically acceptable salt thereof,
- a citrate;
- and
- a carrier;
- wherein the dry powder pharmaceutical composition has a moisture content of between about 3% and about 6%.
Dependencies are inferred from the claim text.