Surface modified ophthalmic devices

A method for making a surface modified ophthalmic device comprising:

• providing an ophthalmic device having a plurality of surface functional groups;
• and
• attaching a lifitegrast or a salt thereof-containing monomer or a lifitegrast or a salt thereof-containing polymer to a surface of the ophthalmic device through the plurality of surface functional groups.

A method for delivering lifitegrast or salt thereof to an eye of a subject, comprising:

• placing a surface modified ophthalmic device in an eye of a subject, wherein the surface modified ophthalmic device comprises an ophthalmic device having a plurality of surface functional groups and a surface coating, the surface coating comprising a lifitegrast or a salt thereof-containing monomer or a lifitegrast or a salt thereof-containing polymer attached to a surface of the ophthalmic device through the plurality of surface functional groups;
• and
• delivering the lifitegrast or salt thereof to the eye of the subject by contacting the ophthalmic device with one of light having a wavelength of about 300 nanometers (nm) to about 700 nm or with an esterases or enzymes on the eye, in a tear film or on a flora of the eye.