A computer readable medium encoded with computer executable instructions, which, when executed by a processor, causes the processor to:
- receive at least a first scout image with a first dose profile and a second scout image with a second dose profile for a patient,
- wherein the first scout image includes a first reference origin, the second scout image includes a second reference origin;
- receive a human reference image that is pre-marked with a set of anatomical regions;
- map anatomical regions between the first scout image and the human reference image and the second scout image and the human reference image;
- sum the first dose profile and the second dose profile based on the mapped anatomical regions between the first and second scout images and the human reference image, independent of the first and second reference origins;
- and
- generate a cumulative dose profile for the patient based on the summed first and second dose profiles.