Determining an efficacy of a treatment program

A method comprising:

• receiving, by processing circuitry, from a medical device, an electrical signal that indicates a parameter of a patient, wherein the medical device includes one or more electrodes and sensing circuitry configured to generate, based on a physiological signal sensed from target tissue of the patient via the one or more electrodes, the electrical signal that indicates the parameter of the patient;
• receiving, by the processing circuitry, data indicating a reference time indicative of beginning administration of a treatment;
• determining, by the processing circuitry, a plurality of parameter values of the parameter based on a portion of the electrical signal corresponding to a period of time including the reference time;
• identifying, by the processing circuitry, based on a first set of parameter values of the plurality of parameter values occurring before the reference time, a reference parameter value;
• calculating, by the processing circuitry, based on a second set of parameter values of the plurality of parameter values occurring after the reference time and based on the reference parameter value, a parameter change value;
• and
• determining, by the processing circuitry, based on the parameter change value, whether an improvement or a worsening of the patient has occurred responsive to the treatment.

A non-transitory computer-readable medium having instructions stored thereon, wherein the instructions are executable by processing circuitry to cause the processing circuitry to:

• receive, from a medical device, an electrical signal that indicates a parameter of a patient, wherein the medical device includes one or more electrodes and sensing circuitry configured to generate, based on a physiological signal sensed from target tissue of the patient via the one or more electrodes, the electrical signal that indicates the parameter of the patient;
• receive data indicating a reference time indicative of beginning administration of a treatment;
• determine a plurality of parameter values of the parameter based on a portion of the electrical signal corresponding to a period of time including the reference time;
• identify, based on a first set of parameter values of the plurality of parameter values occurring before the reference time, a reference parameter value;
• calculate, based on a second set of parameter values of the plurality of parameter values occurring after the reference time and based on the reference parameter value, a parameter change value;
• and
• determine, based on the parameter change value, whether an improvement or a worsening of the patient has occurred responsive to the treatment.