Dissection apparatus

A Dissection apparatus comprising a dissection tool for dissecting biological material from an identified region of interest within a tissue sample disposed on a slide, whereby the apparatus is equipped with a light source for illuminating the tissue sample and an imaging module, having an image sensor and an image processor, which is configured to:

• capture a first image of the tissue sample prior to dissection;
• and
• register an annotated boundary of the ROI onto the first image, which annotated boundary has been identified from a reference image of a corresponding reference sample,
• wherein the imaging module is further configured to capture a second image of the tissue sample after dissection, and wherein the image processor is programmed with an algorithm which executes steps of:
• detecting an achieved dissection boundary, based on a pixelwise comparison of the first and second images, to determine a change in intensity;
• comparing the detected dissection boundary with the registered annotated boundary to determine at least one indicator that is representative of the achieved quality of the dissection result;
• and
• generating a quality report that includes the at least one determined indicator.