Systems and methods for corneal opacity detection using optical coherence tomography

A system comprising:

• a OCT system;
• a logic subsystem;
• and
• a data holding subsystem comprising non-transitory machine-readable instructions stored thereon that are executable by the logic subsystem to:
• obtain an OCT dataset of a cornea, the OCT dataset comprising a plurality of A-scans, each of the A-scans comprising a plurality of pixels extending depth-wise through the cornea and each having a measured signal value;
• segment the pixels of the OCT dataset into two or more anatomic layers;
• divide each of the two or more anatomic layers into a plurality of depth increments;
• associate, for each of the pixels within the two or more anatomic layers, an angle of incidence and a depth;
• for each of the depth increments, identify a first set of pixels whose signal values exceed a threshold calculated using a reflectance model that is dependent on anatomic layer, angle of incidence, and depth;
• and
• generate a map of the first set of pixels.