US 2026/0286573 A1 · 3D PRINTING ELECTROSPINNING SYSTEMS AND METHODS

Abstract

Described are techniques, systems, and methods including those employing electrospinning, printheads including multiple linkers, and a mechanical arm that facilitates a continuous, safe, and efficient fiber and/or fiber mat production system. The printheads may be in fluid communication with a spinneret to form droplets suitable for electrospinning. The electrospun fibers may include complex structures. In some examples, the electrospun fibers may include multiple layers, particles (e.g., microparticles, nanoparticles, etc.) and/or different fiber components with desired structures (e.g., bi-axial fibers, tri-axial fibers, co-axial fibers, co-biaxial fibers, etc.). The electrospun fibers may be disposed in an environmental simulator to mimic the release of a disintegrated test drug in a semi-permeable membrane.

Claims30

Dependent claims

An integrated electrospinning system comprising:

a plurality of supply containers for preparing or storing a respective component comprising a polymer or a non-polymeric excipient, a solvent, or an active pharmaceutical ingredient (API);
a printhead in fluid communication with the plurality of supply containers, the printhead comprising:
a plurality of linkers, wherein each linker is in fluid communication with a supply outlet of one of the plurality of supply containers;
a fluid mixer for mixing components from the plurality of linkers into a mixture;
and
one or more outlets in fluid communication with the fluid mixer;
and
a spinneret in fluid communication with the one or more outlets;
a high-voltage power supply in electrical communication with the spinneret to form electrospun fibers;
and
a collector to collect the electrospun fibers.

8 more elements

Dependencies are inferred from the claim text.

3d printing electrospinning systems and methods

Life of this patent

3d printing electrospinning systems and methods

Life of this patent

Abstract

Claims30