RNA-Based Compositions and Methods for Treating Breast Cancer
AssigneeAvicenna Biotech Research, LLC
InventorsBabak Behnam, Hassan Fazilaty
Life of this patent
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Abstract
This invention provides an RNA molecule that (i) specifically binds to SOX11 mRNA, SNAI1 mRNA, SNAI2 mRNA, ZEB1 mRNA, CCNB1 mRNA, CCNB2 mRNA, CCNA2 mRNA, CDK1 mRNA, SPANXA1 mRNA, SPANXB1 mRNA, POSTN mRNA, or MMP2 mRNA, and (ii) has a 3′ residue that is either U or A. This invention also provides related siRNA molecules, therapeutic compositions, and methods of using same to treat breast cancer.
Claims17
-39. (canceled)
An RNA molecule that (i) specifically binds to an mRNA selected from the group consisting of SOX11 mRNA, SNAI1 mRNA, SNAI2 mRNA, ZEB1 mRNA, CCNB1 mRNA, CCNB2 mRNA, CCNA2 mRNA, CDK1 mRNA, SPANXA1 mRNA, SPANXB1 mRNA, POSTN mRNA, and MMP2 mRNA, and (ii) has a 3′ residue that is either U or A.
Dependencies are inferred from the claim text.