Compositions and methods including rna-binding proteins
AssigneeRegents of the University of Minnesota
InventorsWendy Ryan Gordon, Adam Trey Smiley, Kassidy J. Tompkins
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Abstract
An RNA-binding protein includes a substitution mutation to a semi-conserved domain, said semi-conserved domain including the amino acid sequence of SEQ ID NO:5. 21. The RNA-binding protein may be an HUH endonuclease, such as a virally-derived HUH endonuclease, such as PCV2. A fusion protein includes an RNA-binding protein and a protein involved in gene editing. A composition includes an RNA-binding protein or a fusion protein including an RNA-binding protein.
Claims25
An RNA-binding protein comprising a substitution mutation to a semi-conserved domain, said semi-conserved domain comprising an amino acid sequence comprising SEQ ID NO:5.
Dependencies are inferred from the claim text.