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US 2026/0286007 A1Published application
Anti-tmprss6 antibodies and uses thereof
AssigneeDisc Medicine, Inc.
InventorsWill Savage, Brian MacDonald, Min Wu
Life of this patent
Estimating the term…
Abstract
Aspects of the disclosure provide anti-TMPRSS6 antibodies and methods of using the same for promoting hepcidin expression, and treating iron overload associated conditions, such as hemochromatosis, sickle cell disease, thalassemia, hemolysis, Diamond-Blackfan anemia, myelodysplastic syndrome (MDS), blood transfusion.
Claims2
1-21. (canceled)
A kit for treating an iron overload-associated condition in a subject in need thereof, the kit comprising:
- (a) a container comprising a pharmaceutical composition comprising an anti-transmembrane serine protease 6 (TMPRSS6) antibody or an antigen-binding fragment thereof,
- wherein the anti-TMPRSS6 antibody comprises the HC CDR1, HC CDR2, HC CDR3, LC CDR1, LC CDR2, and LC CDR3 of any one of the antibodies set forth in Table 1;
- and
- (b) instructions for administering the pharmaceutical composition to the subject.
1 more element
Dependencies are inferred from the claim text.