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US 2026/0285919 A1Published application
Recombinant peptides and compositions thereof for pain management
AssigneeUniversity of Rochester
InventorsDavid MACLEAN, Kyle BERGER
Life of this patent
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Abstract
A recombinant peptide comprising a modified human Hila C lobe sequence, wherein the peptide inhibits an activity of human ASIC1b receptors. A method for treating pain in a subject, comprising the step of administering to the subject an effective amount of a pharmaceutical composition comprising the recombinant peptide.
Claims22
A recombinant peptide comprising a modified Hila C lobe sequence, wherein the peptide inhibits an activity of human ASIC1b receptors.
-11. (canceled)
A pharmaceutical composition, comprising:
- (1) a recombinant peptide comprising a modified Hila C lobe sequence, or a peptide conjugate comprising the recombinant peptide comprising a modified Hila C lobe sequence and a conjugation partner, or an expression vector encoding the recombinant peptide comprising a modified Hila C lobe sequence;
- and
- (2) a pharmaceutically acceptable carrier,
- wherein the recombinant peptide inhibits an activity of human ASIC1b receptors.
1 more element
(canceled)
Dependencies are inferred from the claim text.