Peptides for antimicrobial therapy

Abstract

Disclosed is an antimicrobial peptide comprising the sequence IGKX1FX2RIVX3RKX4RFLX5X6LVRPLX7 (SEQ ID NO: 7), wherein each of X1, X2, X3, X4, X5, X6, and X7 is an amino acid independently selected from the group consisting of E, K, R, L, I, V, F, A, W, V and P, preferably from the group consisting of E, K, R, L, I, V, F, A, W and V, more preferably from the group consisting of E, K, R, L, W and V. Optionally, one amino acid in this sequence selected from the group of L, V, F, A, I, W, Y or Q, with the exception of X1-X7, is replaced by another amino acid selected from said group or by P. Particularly preferred peptides are IGKEFKRIVERKWRFLRELVRPLR (SEQ ID NO: 2), IGKKFKRIVRRKKRFLRKLVRPLR (SEQ ID NO: 3), IGKEFKRIVERKWRFLRKLVRPLR (SEQ ID NO: 4), IGKEFLRIVERKWRFLRKLVRPLL (SEQ ID NO: 5) and IGKEFLRIVERKWRFLVKLVRPLL (SEQ ID NO: 6).

Dependencies are inferred from the claim text.