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US 2026/0285871 A1Published application
Polymorphic Compounds and Uses Thereof
AssigneeTyra Biosciences, Inc.
InventorsPiyush PATEL, Robert L. HUDKINS, Sathyanarayana Reddy Perumalla
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Abstract
The present invention provides salt forms, and compositions and methods thereof, useful for treating various conditions, such as cancer, by the administration of small molecule therapeutics acting as kinase inhibitors.
Claims63
Compound 2:
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A compound selected from:
- Compound 1:
- or a crystalline form thereof;
- Compound 3:
- or a crystalline form thereof;
- Compound 4:
- or a crystalline form thereof;
- Compound 5:
- or a crystalline form thereof;
- Compound 6:
- or a crystalline form thereof;
- Compound 7:
- or a crystalline form thereof;
- Compound 8:
- or a crystalline form thereof;
- Compound 9:
- or a crystalline form thereof;
- Compound 10:
- or a crystalline form thereof;
- Compound 11:
- or a crystalline form thereof;
- Compound 12:
- or a crystalline form thereof;
- Compound 13:
- or a crystalline form thereof;
- or
- Compound 14:
- or a crystalline form thereof;
- or
- Compound A:
- of crystalline Form I, II, III, IV, V, VI, VII or VIII;
- or
- Compound 23:
- or a crystalline form thereof;
- or
- Compound 24:
- or a crystalline form thereof;
- or
- Compound 25:
- or a crystalline form thereof;
- or
- Compound 26:
- or a crystalline form thereof.
39 more elements
A method for preparing a salt compound of the formula X:
- comprising steps of:
- combining A:
- with a suitable acid and optionally a solvent under conditions suitable for producing the compound of formula X.
Dependencies are inferred from the claim text.