Bicyclic and heterocyclic amide compounds

A compound of Formula (VIII):

• or a pharmaceutically acceptable salt thereof, wherein:
• n is 0 or 1;
• R1 is halogen, cyano, —OH, —O(C1-C6 alkyl), —NH2, —NH(C1-C6 alkyl), —N(C1-C6 alkyl)2, or C1-C6 alkyl, wherein the C1-C6 alkyl is optionally substituted with one or more halogen, cyano, —OH, —NH2, —NHC(═O)(C1-C6 alkyl), —NHS(═O)2(C1-C6 alkyl), or —C(═O)NH2;
• R2a is C1-C6 alkyl optionally substituted with one or more halogen, cyano, —OH, or —NH2;
• R2b is H or C1-C6 alkyl, wherein the C1-C6 alkyl is optionally substituted with one or more halogen;
• R2c is H or C1-C6 alkyl, wherein the C1-C6 alkyl is optionally substituted with one or more halogen;
• R2d is H;
• or R2a and R2d together form C1-C6 alkylene optionally substituted with one or more halogen;
• Y is C3-C8 cycloalkyl, C6-C10 aryl, or 5- to 10-membered heteroaryl, wherein the C3-C8 cycloalkyl, C6-C10 aryl, or 5- to 10-membered heteroaryl is optionally substituted with one or more RYa;
• each RYa independently is oxo, halogen, cyano, —OH, —O(C1-C6 alkyl), —NH2, —NH(C1-C6 alkyl), —N(C1-C6 alkyl)2, —C(═O)—H, —C(═O)—OH, —C(═O)—O(C1-C6 alkyl), —C(═O)—NH2, —C(═O)—NH(C1-C6 alkyl), —C(═O)—N(C1-C6 alkyl)2, C1-C6 alkyl, C2-C6 alkenyl, or C2-C6 alkynyl, wherein the C1-C6 alkyl, C2-C6 alkenyl, or C2-C6 alkynyl is optionally substituted with one or more RYb;
• each RYb independently is oxo, halogen, cyano, —OH, —O(C1-C6 alkyl), —NH2, —NH(C1-C6 alkyl), —N(C1-C6 alkyl)2, —C(═O)—H, —C(═O)—OH, —C(═O)—O(C1-C6 alkyl), —C(═O)—NH2, —C(═O)—NH(C1-C6 alkyl), or —C(═O)—N(C1-C6 alkyl)2;
• ring A is
• where * indicates connectivity to the carbonyl group at triazolopyridine;
• ring B is H, C3-C6 cycloalkyl, 4- to 10-membered heterocyclyl, C6-C10 aryl, or 5- to 10-membered heteroaryl;
• Z is absent, —CH2-, —O—, or —C(═O)—;
• each RTa independently is oxo, halogen, cyano, —OH, —ORTb, —NH2, —NHRTb, —N(RTb)2, —C(═O)—H, —C(═O)—RTb, —C(═O)—OH, —C(═O)—ORTb, —C(═O)—NH2, —C(═O)—NHRTb, —C(═O)—N(RTb)2, —S(═O)2—RTb, —S(═O)(═NH)—RTb, C1-C6 alkyl, C1-C6 haloalkyl, C2-C6 alkenyl, C2-C6 haloalkenyl, C2-C6 alkynyl, or C2-C6 alkynyl;
• each RTb is C1-C6 alkyl, C1-C6 haloalkyl, C2-C6 alkenyl, C2-C6 haloalkenyl, C2-C6 alkynyl, or C2-C6 alkynyl;
• and
• each RTb1 independently is oxo, halogen, cyano, —OH, —O(C1-C6 alkyl), —NH2, —NH(C1-C6 alkyl), —N(C1-C6 alkyl)2, —C(═O)—H, —C(═O)—OH, —C(═O)—O(C1-C6 alkyl), —C(═O)—NH2, —C(═O)—NH(C1-C6 alkyl), —C(═O)—N(C1-C6 alkyl)2, C1-C6 alkyl, C2-C6 alkenyl, or C2-C6 alkynyl;
• wherein when B is H, Z is absent.