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US 2026/0285830 A1Published application
CRYSTALLINE METHIONINE ADENOSYLTRANSFERASE 2a (MAT2A) INHIBITOR AND USES THEREOF
AssigneeInsilico Medicine IP Limited
InventorsXing LIANG, Hui WANG, Yushu YIN, Congcong ZHU, Chiachun CHEN, Xiao DING
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Abstract
Described herein are crystalline forms of a small molecule methionine adenosyltransferase 2a (MAT2A) inhibitor, as well as pharmaceutical compositions thereof, and methods of use thereof in the treatment of diseases or conditions that would benefit from treatment with methionine adenosyltransferase 2a (MAT2A) inhibitor.
Claims26
A solid state form of 5-methoxy-1-(2-methylpyridin-3-yl)-4-(prop-2-yn-1-ylamino)-7-(trifluoromethyl) quinazolin-2 (1H)-one:
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.