US 2026/0285809 A1 · CRYSTAL OF N-(BENZOYL)-PHENYLALANINE COMPOUND, AND PHARMACEUTICAL COMPOSITION THEREOF, AND PREPARATION METHOD THEREFOR AND USE THEREOF

Abstract

The present invention relates to crystals of N-(benzoyl)-phenylalanine compounds as well as their pharmaceutical compositions, preparation methods and purposes. Specifically, the compounds are shown by Formula (I) and (II). The crystals shown by Formula (I) and (II) exist in the forms of Crystal Form A and Crystal Form B, respectively. Both crystal forms feature high stability, high preparation reproducibility and excellent operability, and have important application values in prophylactizing and/or treating diseases associated with α4β7 integrin.

Claims21

Dependent claims

A compound shown by Formula (I),

which exists in the form of crystal form A;
under Cu-Kα radiation, an XRPD pattern of which shows characteristic peaks at 2θ values of 10.4±0.2°, 13.1±0.2°, 13.6±0.2°, 18.8±0.2°, 19.6±0.2°, 20.2±0.2°, 21.9±0.2° and 22.1±0.2°.

Dependencies are inferred from the claim text.

Crystal of n-(benzoyl)-phenylalanine compound, and pharmaceutical composition thereof, and preparation method therefor and use thereof

Life of this patent

Crystal of n-(benzoyl)-phenylalanine compound, and pharmaceutical composition thereof, and preparation method therefor and use thereof

Life of this patent

Abstract

Claims21