Methods for treating neuromuscular diseases
AssigneeHoffmann-La Roche Inc.
InventorsXing CHEN, Juergen GOTTOWIK, Slawomir OPALKA, Maryam OSKOUI, David HERZIG
Life of this patent
Estimating the term…
Loading patent…
AssigneeHoffmann-La Roche Inc.
InventorsXing CHEN, Juergen GOTTOWIK, Slawomir OPALKA, Maryam OSKOUI, David HERZIG
Estimating the term…
The present invention relates to computer-implemented methods comprising: providing a user interface to a subject that has been diagnosed as having a neuromuscular disease or disorder and optionally undergoing treatment with a therapeutic compound or composition for the treatment of the neuromuscular disease or disorder; receiving movement data comprising coordinates of a plurality of joints of the subject or data derived therefrom, at a plurality of time points, and in response to receiving movement data satisfying a set of predetermined criteria, triggering a change in the user interface, wherein the change is specific to the set of predetermined criteria satisfied and wherein the set of predetermined criteria is selected from a plurality of sets of predetermined criteria, each set identifying a predetermined movement. Related systems and digital physiotherapy methods and methods for treating a subject with a neuromuscular disorder using the digital physiotherapy method are also described.
A computer-implemented method comprising:
The method of any preceding claim, wherein the plurality of sets of predetermined criteria comprise:
The method of any preceding claim, wherein one or more of the predetermined criteria apply to angles between predetermined vectors derived from one or more joints or to projections of angles between predetermined vectors on predetermined body planes and/or wherein each set of predetermined criteria is individually selected from:
The method of any preceding claim, wherein at least one criterion applies to an angle between two predetermined vectors derived from one or more joints or to the projection of an angle between two predetermined vectors on a predetermined body plane, and wherein the method comprises calibrating the at least one criterion by recording movement data of the subject while the subject is performing the movement associated with the predetermined criterion and identifying an expected range of the angle or the angle projection while the subject is performing the movement associated with the predetermined criterion.
The method of any preceding claim, wherein the plurality of sets of predetermined criteria comprise one or more of:
The method of any preceding claim, wherein the plurality of joints include one or more or all of a plurality of locations that aligns with a subject's:
The method of any preceding claim, wherein the subject has a neuromuscular disease or disorder selected from:
A method of improving, stabilising or reducing the degradation in a motor function score in a subject undergoing treatment with a therapeutic compound or composition for treating a neuromuscular disease or disorder, and/or increasing the likelihood of continued administration of a physiotherapy dosage regimen, wherein continued administration of a physiotherapy dosage regimen refers to adherence to the physiotherapy dosage regimen for at least 3 months, at least 6 months, at least 9 months or at least 12 months, wherein the method comprises implementing a computer-implemented method for digital physiotherapy comprising the steps of:
Dependencies are inferred from the claim text.