Search and optimization algorithms for exploring novel stimulation patterns
AssigneeBoston Scientific Neuromodulation Corporation
InventorsJianwen Gu, Hemant S Bokil, Mahsa Malekmohammadi
Life of this patent
Estimating the term…
Abstract
Methods and systems configured for identifying effective therapy regimens and optimizing output settings. One or more test stimulations are issued to a patient having a neuromodulation system, and a relationship between at least one test parameter and at least on therapy effect is identified. Optimization uses this relationship to configure therapy parameters to cause a desired therapy effect.
Claims20
A method of treating a patient with an implantable neuromodulation system having a pulse generator and at least one lead having a plurality of electrodes thereon, the method comprising:
- delivering a first programmed therapy to the patient with first parameters using the pulse generator and at least one lead;
- observing a first response to the delivered first programmed therapy;
- delivering a second programmed therapy to the patient with second parameters using the pulse generator and at least one lead, the second parameters having at least one changed parameter relative to the first parameters;
- observing a second response to the delivered second programmed therapy;
- identifying a relationship between the changed parameter and a therapy response from the first programmed therapy, the first response, the second programmed therapy, and the second response;
- calculating an optimized therapy using the identified relationship;
- and
- delivering the optimized therapy to the patient.
A method of treating a patient with an implantable neuromodulation system having a pulse generator and at least one lead having a plurality of electrodes thereon, the method comprising:
- testing a first programmed therapy by:
- delivering the first programmed therapy to the patient;
- observing a first change in a chosen symptom of the patient;
- ceasing to deliver the first programmed therapy;
- observing a second change in the chosen symptom of the patient;
- and
- determining a first duration related to the first programmed therapy and the chosen symptom;
- testing a second programmed therapy by:
- delivering the second programmed therapy to the patient;
- observing a third change in the chosen symptom of the patient;
- ceasing to deliver the second programmed therapy;
- observing a fourth change in the chosen symptom of the patient;
- and
- determining a second duration related to the first programmed therapy and the chosen symptom;
- identifying a relationship between a therapy parameter and a therapy result from the first programmed therapy, the first duration, the second programmed therapy, and the second duration;
- calculating an optimized therapy using the identified relationship;
- and
- delivering the optimized therapy to the patient.
An implantable neuromodulation system comprising:
- an implantable pulse generator;
- at least one implantable lead having a plurality of electrodes thereon;
- and
- an external programmer adapted to communicate with and provide therapy instructions to the implantable pulse generator, wherein the system is configured to:
- deliver a first programmed therapy to the patient with first parameters using the pulse generator and at least one lead;
- observe a first response to the delivered first programmed therapy;
- deliver a second programmed therapy to the patient with second parameters using the pulse generator and at least one lead, the second parameters having at least one changed parameter relative to the first parameters;
- observe a second response to the delivered second programmed therapy;
- identify a relationship between the changed parameter and a therapy response from the first programmed therapy, the first response, the second programmed therapy, and the second response;
- calculate an optimized therapy using the identified relationship;
- and
- deliver the optimized therapy to the patient.
Dependencies are inferred from the claim text.