Tissue restoration composition
AssigneeDexlevo Inc.
InventorsJae Won YU, Myung Seob SHIM, Jun Bae KIM
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Abstract
A tissue restoration composition in a colloidal phase, includes a copolymer in which a hydrophobic biocompatible polymer and a hydrophilic biocompatible polymer are polymerized and which is dispersed in water. The colloidal phase is prepared by adding the copolymer to water, followed by heating to a temperature between a melting point of the copolymer and a boiling point of the water, the colloidal phase has a viscosity of 20-200,000 cP.
Claims7
1-12. (canceled)
A tissue restoration composition in colloidal phase, comprising a copolymer in which a hydrophobic biocompatible polymer and a hydrophilic biocompatible polymer are polymerized and which is dispersed in water,
- wherein the colloidal phase is prepared by adding the copolymer to water, followed by heating to a temperature between a melting point of the copolymer and a boiling point of the water, and
- wherein the colloidal phase has a viscosity of 20-200,000 cP,
- wherein the hydrophobic biocompatible polymer is at least any one polymer selected from the group consisting of polyglycolic acid, polycaprolactone, poly lactic acid, polydioxanone, poly(trimethylene carbonate), polyhydroxybutyrate, and a copolymer including the same, and
- wherein the hydrophilic biocompatible polymer is at least any one polymer selected from the group consisting of methoxy polyethylene glycol, dihydroxy polyethylene glycol, mono-alkoxy polyethylene glycol, and polyethylene glycol,
- wherein the concentration of the copolymer in a colloidal solution is 10-50 wt %, and
- wherein the hydrophilic biocompatible polymer has a molecular weight of 2,000-50,000 g/mol, the hydrophobic biocompatible polymer has a molecular weight of 2,000-70,000 g/mol, and the copolymer has molecular weight of 4,000-120,000 g/mol.
Dependencies are inferred from the claim text.