Back to results
US 2026/0284198 A1Published application
Methods and compositions for targeted delivery by polymersomes
AssigneeRock Biomedical, Inc.
InventorsChi-Huey WONG, Jeng-Shin LEE, Chen-Yo FAN, Szu-Wen WANG
Life of this patent
Estimating the term…
Abstract
The present disclosure relates to a copolymer and a polymersome for targeted delivery of biomolecules to a living organism. Hie exemplary copolymer comprises an initiator block, a propagator block, and a linkage connecting the initiator block and the propagator block. The initiator block comprises a glycan head configured to provide a targeted delivery, and the propagator block comprises a functional moiety configured to provide desired properties for the polymersome.
Claims30
A copolymer for forming a polymersome, wherein the copolymer comprises:
- an initiator block, comprising a glycan head;
- a propagator block, comprising a functional moiety, which comprises a guanidine group, a zwitterion group, a diethylene triamine, or a combination thereof;
- and
- a linkage, covalently connecting the initiator block and the propagator block, wherein the linkage comprises a disulfide bond.
1 more element
Dependencies are inferred from the claim text.