A broadly protective prophylactic vaccine against pseudomonas aeruginosa
AssigneesUniversity of Kansas, University of Maryland, Baltimore
InventorsWendy L. PICKING, William D. PICKING, Robert K. ERNST
Life of this patent
Estimating the term…
Abstract
Disclosed are compositions comprising a fusion polypeptide comprising i) a fusion of a needle tip protein or an antigenic fragment thereof and/or a translocator protein or an antigenic fragment thereof from a Type III secretion system (T3SS) of a Gram negative bacteria and ii) the A1 subunit of the labile toxin (LTA1) from enterotoxigenic Escherichia coli or cholera toxin. and methods of their use.
Claims18
A fusion polypeptide comprising i) a fusion of a needle tip protein or an antigenic fragment thereof and/or a translocator protein or an antigenic fragment thereof from a Type III secretion system (T3SS) of a Gram negative bacteria and ii) a double mutant labile toxin (dmLT) or an antigenic fragment thereof from Enterotoxigenic Escherichia coli or cholera toxin or an antigenic fragment thereof.
Dependencies are inferred from the claim text.