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US 2026/0284160 A1Published application
Method and composition for treating arginase 1 deficiency
AssigneeImmedica Pharma AB
InventorsScott W. ROWLINSON, Anthony G. QUINN, Ann LOWE, David LOWE
Life of this patent
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Abstract
A method and composition to treat a subject with arginase I (ARGI) deficiency (ARG 1-D) and to rapidly reduce the levels of at least one of arginine and/or a guanidino compound in the subject.
Claims20
A method for reducing a plasma level of arginine and at least one compound selected from the group consisting of:
- N-α-acetylarginine (NAArg), argininic acid (ArgA), α-keto-β-guanidinovaleric acid (GVA), and guanidinoacetic acid (GAA), to a normal level in a subject with Arginase 1 (ARG1) deficiency (ARG1-D), the method comprising administering to the subject a composition comprising a therapeutically effective amount of a pegylated arginase.
Dependencies are inferred from the claim text.