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US 2026/0284154 A1Published application
Composition and methods for modulation of elovl2
AssigneesYouhealth Biotech, Limited, The Regents of the University of California
InventorsKang Zhang, Xin Li, Gen Li
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Abstract
Disclosed herein are therapeutic agents capable of increasing the expression level of an epigenetic marker described herein. Also described herein are therapeutic agents that reduce or slow-down an aging phenotype.
Claims16
A method of reducing or slowing down an aging phenotype in a subject in need thereof, comprising administering to the subject a composition comprising a therapeutic agent that reduces or slows down the aging phenotype,
- wherein the therapeutic agent comprises a vector comprising a polynucleotide encoding ELOVL2 or a functionally active fragment thereof, and
- wherein the vector is a viral vector selected from the group consisting of an alphavirus-based vector, a herpesvirus-based vector, a retrovirus-based vector, a lentivirus-based vector, and a vaccinia virus-based vector.
Dependencies are inferred from the claim text.