Compositions and Methods for Treatment of Protease Mediated Disease
AssigneeThe Regents of the University of California
InventorsMichael E. Selsted, Dat Q. Tran
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Abstract
A method is provided for a condition related to the activity of a protease through the administration of a θ-defensin, analog, or derivative is described. Suitable proteases include metalloproteases and cysteine proteases such as Cathepsin-C. The θ-defensin, analog, or derivative can be effectively administered parenterally, topically, or orally.
Claims7
1-13. (canceled)
A peptide having amino acid sequence of SEQ ID NO:
- 12.
A method of treating inflammation, an inflammatory disease, or an autoimmune disease in subject in need thereof, the method comprising administering to the subject a peptide having SEQ ID NO:
- 12.
A method of treating cancer in a subject in need thereof, the method comprising administering to the subject a peptide having SEQ ID NO:
- 12.
Dependencies are inferred from the claim text.