Lactobacillus compositions for treating type 2 diabetes
OwnerGraciela Liliana LORCA, Claudio F. GONZALEZinventors
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Abstract
It is disclosed herein that administration of Lactobacillus johnsonii N6.2 has a remarkable beneficial effect on diabetes symptoms in DB/DB mice. Based on these results, provided are methods of treat type 2 diabetes involving the administration of L. johnsonii N6.2. In addition, methods of treating or ameliorating steatosis and diabetic nephropathy are disclosed.
Claims30
A method for treating type 2 diabetes (T2D) in a subject in need, wherein said method comprises administering to the subject in need an effective amount of a composition comprising a Lactobacillus sp wherein said composition, optionally, further comprises a carrier.
The method, according to any of claims 1, 3-9, 13 and 14, wherein the subject in need has T2D.
The method, according to any of claims 1, 3-9, 13 and 14, wherein the subject in need is at risk for T2D.
A capsule, optionally a DR capsule, comprising a lyophilized amount of a Lactobacillus sp and a carrier contained within the capsule, wherein the capsule comprises a shell that is, optionally, comprised of hydrophilic cellulose derivative and an anionic polymer.
A method of treating fatty liver disease in a subject in need, wherein said method comprises administering to the subject in need an effective amount of a composition comprising a Lactobacillus sp wherein said composition, optionally, further comprises a carrier.
A method of treating diabetic nephropathy in a subject in need, wherein said method comprises administering to the subject in need an effective amount of a composition comprising a Lactobacillus sp wherein said composition, optionally, further comprises a carrier.
Dependencies are inferred from the claim text.