Back to results
US 2026/0284038 A1Published application
Treatment of prurigo nodularis
AssigneeTrevi Therapeutics, Inc.
InventorsThomas SCIASCIA, Jennifer L. GOOD, Amale HAWI
Life of this patent
Estimating the term…
Abstract
The present invention relates to methods for treating prurigo nodularis with anti-pruritic compositions, wherein the method provides a therapeutic effect in a patient.
Claims30
A method of treating prurigo nodularis, comprising:
- (a) a titration period, comprising administering nalbuphine or a pharmaceutically acceptable salt or ester thereof to a patient in need thereof according to the following dose schedule:
- Day
- AM dosage (mg)
- PM dosage (mg)
- Day 1
- 0
- 30
- Day 2
- 0
- 30
- Day 3
- 30
- 30
- Day 4
- 30
- 30
- Day 5
- 30
- 60
- Day 6
- 60
- 60
- Day 7
- 60
- 60
- Day 8
- 60
- 90
- Day 9
- 90
- 90
- Day 10
- 90
- 90
- Day 11
- 90
- 120
- Day 12
- 120
- 120
- Day 13
- 120
- 120
- Day 14
- 120
- 180
- and
- (b) a treatment period, comprising administering a daily dose of about 360 mg of nalbuphine or a pharmaceutically acceptable salt or ester thereof to the patient for at least a week following the titration period.
45 more elements
Dependencies are inferred from the claim text.