Methods of treating heart failure
AssigneeChildren's Medical Center Corporation
InventorsDenisa D. WAGNER, Lukas A. HEGER, Nicolas SCHOMMER
Life of this patent
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Abstract
The technology described herein is directed to administering a PAD4 inhibitor to treat a subject diagnosed with having, or at risk of having heart failure, e.g., HFpEF, diastolic heart failure, or diastolic dysfunction. Compositions comprising a PAD4 inhibitor is also described herein.
Claims26
A method of treating or preventing heart failure comprising administering a PAD4 inhibitor to a subject in need thereof.
A method of treating or preventing heart failure, the method comprising administering a PAD4 inhibitor to a subject in need thereof, wherein the PAD4 inhibitor is JBI-589 or a derivative thereof.
A composition for the treatment or prevention of heart failure comprising a PAD4 inhibitor and a pharmaceutically acceptable carrier.
A composition for treating or preventing heart failure, the composition comprising a PAD4 inhibitor, wherein the PAD4 inhibitor is JBI-589 or a derivative thereof.
Use of a composition comprising a PAD4 inhibitor for the treatment of prevention of heart failure, wherein the PAD4 inhibitor is JBI-589 or a derivative thereof.
Dependencies are inferred from the claim text.