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US 2026/0283964 A1Published application
Method for manufacturing pharmaceutical mini-tablets
AssigneePurdue Research Foundation
InventorsVarun Sundarkumar, Zoltan Kalman Nagy, Gintaras V. Reklaitis, Wanning Wang
Life of this patent
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Abstract
A method for manufacturing pharmaceutical mini-tablets with a low dosage and high content of uniformity by employing drop-on-demand three-dimensional printing; a printed mini-tablet manufactured in accordance with the method; and a combination of two or more printed mini-tablets.
Claims15
A method for manufacturing mini-tablets which method comprises:
- i) preparing a drug formulation by mixing an active pharmaceutical ingredient (API) and one or more first excipients;
- ii) heating the drug formulation either to obtain a melt-based suspension drug formulation or a melt-based solution drug formulation;
- iii) printing a drop of the melt-based drug formulation of step (ii) using a drop-on-demand (DoD) printing system;
- iv) collecting a printed drop of the drug formulation in a solidification bath to obtain a solidified drop of the drug formulation;
- and
- v) extracting, washing, and drying the solidified drop of the drug formulation, whereupon the mini-tablet is manufactured.
3 more elements
Dependencies are inferred from the claim text.