Analyte monitoring systems with on-body devices having improved wear duration

An on-body device, comprising:

• a sensor;
• electronics configured to receive a signal from the sensor, the signal indicative of a level of an analyte of a user;
• a housing configured to retain the electronics;
• and
• an adhesive patch adhesively coupled with the housing,
• wherein the sensor comprises:
• a proximal portion configured to be positioned above skin of the user and to be electrically coupled with the electronics;
• and
• a distal portion configured to be transcutaneously positioned through the user's skin and in contact with a bodily fluid of the user,
• wherein the distal portion of the sensor is further configured to detect an analyte in the bodily fluid and output the signal to the electronics;
• wherein the housing is adapted to permit egress of moisture from an area adjacent the housing and the housing comprises a base having a first surface for facing a skin surface of the user, wherein the housing comprises one or more first channels along the first surface and one or more second channels along the first surface, wherein the one or more first channels and the one or more second channels are configured to permit egress of moisture from an area adjacent the first surface, and
• wherein the one or more second channels comprises a curved channel having two ends that terminate at a peripheral edge of the base.