Colorectal cancer detection
AssigneeDxcover Limited
InventorsMatthew J. Baker, David Palmer, James Cameron, Rose G. McHardy
Life of this patent
Estimating the term…
Abstract
A method of determining or detecting whether a subject has adenoma, comprises performing a vibrational (e.g., IR) spectroscopic analysis on a blood sample from the subject, to produce a spectroscopic signature characteristic of the blood sample, wherein said spectroscopic signature of the blood sample is analysed against representative signatures from previous subjects with and without adenoma, in order to detect whether or not the subject has adenoma, based upon the spectroscopic signature obtained from the subject
Claims20
A method of determining or detecting whether a subject suspected of having a type of cancer has either adenoma or cancer irrespective of the stage of cancer, the method comprising:
- performing an infrared (IR) spectroscopic analysis on a blood sample from the subject, to produce a spectroscopic signature characteristic of the blood sample, wherein said spectroscopic signature of the blood sample is analysed against representative signatures from previous subjects with and without cancer and with and without adenoma, in order to detect whether or not the subject has either cancer or adenoma, based upon the spectroscopic signature obtained from the subject.
A method of determining or detecting whether a subject suspected of having a type of cancer has adenoma, the method comprising:
- performing an infrared (IR) spectroscopic analysis on a blood sample from the subject, to produce a spectroscopic signature characteristic of the blood sample, wherein said spectroscopic signature of the blood sample is analysed against representative signatures from previous subjects with and without adenoma, in order to detect whether or not the subject has adenoma, based upon the spectroscopic signature obtained from the subject.
A method of determining or detecting whether a subject suspected of having a type of cancer has either advanced adenoma or cancer irrespective of the stage of cancer, the method comprising:
- performing an infrared (IR) spectroscopic analysis on a blood sample from the subject, to produce a spectroscopic signature characteristic of the blood sample, wherein said spectroscopic signature of the blood sample is analysed against representative signatures from previous subjects with and without cancer and with and without advanced adenoma, in order to detect whether or not the subject has either cancer or advanced adenoma, based upon the spectroscopic signature obtained from the subject.
(canceled)
A trained model configured to receive an input comprising a spectroscopic signature of an infrared (IR) spectroscopic analysis performed on a blood sample from a subject and to provide an output representative of whether or not the subject has either adenoma or cancer.
-18. (canceled)
A method of training a model comprising:
- receiving a plurality of data sets representing spectroscopic signatures for a plurality of subjects obtained from an infrared (IR) spectroscopic analysis on blood samples from the subjects;
- receiving cancer data and adenoma data indicating for at least some of the subjects whether the subject has cancer or adenoma;
- and
- training the model to determine a probability of whether a patient has cancer or adenoma based on a spectroscopic signature for the patient, wherein
- some of the subjects have cancer and some of the subjects have adenoma.
-21. (canceled)
Dependencies are inferred from the claim text.