Automated cell passaging

Abstract

Disclosed are methods of identifying the location of the of an extracellular matrix structure on the surface of a culture plate with a substantially automated process. Also disclosed are automated methods for removal of cells from an extracellular matrix structure within which the cells are grown. The method includes providing cultured cells in the extracellular matrix structure on a surface of a culture plate; and using a substantially automated process, disrupting the extracellular matrix structure at an X, Y position of the extracellular matrix structure on the surface of the culture plate with a pipette tip associated with a liquid handler.

Dependencies are inferred from the claim text.